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Insulin enhances glucose uptake into skeletal muscle and adipose tissues by activating the PI3K/Akt signalling pathway, regulating GLUT4 trafficking from intracellular compartments (known as the GLUT4-storage compartment (GSC), or GLUT4-storage vesicles (GSVs)) to the plasma membrane (PM) in adipocytes, or sarcolemma and transverse tubule membrane in myocytes (Figure 1)

Diet soda and artificial sweeteners: evaluating risks, benefits, and the importance of context [47:00]

Noctor G, Gomez L, Vanacker H, Foyer CH (2002) Interactions between biosynthesis, compartmentation and transport in the control of glutathione homeostasis and signalling